• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 4.306

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr18_+_59593591	19.374	NM_003784	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr17_-_37022465	18.628	NM_005557	KRT16	keratin 16
chr3_+_11153778	17.948	NM_001098213	HRH1	histamine receptor H1
chr9_-_90456824	16.721	NM_001100111	LOC286238	hypothetical protein LOC286238
chr5_+_150000394	15.891	NM_001109974 NM_007286	SYNPO	synaptopodin
chr21_+_29439768	15.106		C21orf7	chromosome 21 open reading frame 7
chr13_-_35327798	14.862	NM_001195415 NM_001195416 NM_001195430	DCLK1	doublecortin-like kinase 1
chr1_+_221955876	14.856	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr8_+_22900863	14.800	NM_001160036	RHOBTB2	Rho-related BTB domain containing 2
chr6_+_47774247	14.267	NM_153838	GPR115	G protein-coupled receptor 115
chr11_-_102219450	14.162	NM_002422	MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr12_-_68369322	13.410	NM_152439	BEST3	bestrophin 3
chr7_+_72883128	13.317	NM_001305	CLDN4	claudin 4
chr1_+_17719405	13.240		ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr17_-_36469869	13.172	NM_001165252	LOC730755	keratin associated protein 2-4-like
chr17_+_21131940	13.082	NM_002756	MAP2K3	mitogen-activated protein kinase kinase 3
chr18_+_19947314	12.967		TTC39C	tetratricopeptide repeat domain 39C
chr13_+_77007809	12.358	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr3_-_11585264	12.226	NM_001128221	VGLL4	vestigial like 4 (Drosophila)
chr5_+_140848905	12.181	NM_018929 NM_032407	PCDHGC5	protocadherin gamma subfamily C, 5
chr14_-_104507862	11.939		AHNAK2	AHNAK nucleoprotein 2
chr12_+_13240868	11.880	NM_001423	EMP1	epithelial membrane protein 1
chr8_-_38505331	11.527	NM_207412	C8orf86	chromosome 8 open reading frame 86
chr5_+_147562531	11.476	NM_001195290 NM_205841	SPINK6	serine peptidase inhibitor, Kazal type 6
chr17_-_36996611	11.302	NM_000526	KRT14	keratin 14
chr12_-_51173238	11.236	NM_005554	KRT6A	keratin 6A
chr20_-_17487480	11.171	NM_001161705	BFSP1	beaded filament structural protein 1, filensin
chr3_+_57069508	11.137	NM_181727	SPATA12	spermatogenesis associated 12
chr14_+_95792299	10.979	NM_000710	BDKRB1	bradykinin receptor B1
chr4_+_120276386	10.904	NM_016599	MYOZ2	myozenin 2
chr7_-_135083906	10.555	NM_205855	FAM180A	family with sequence similarity 180, member A
chr15_+_38849450	10.466	NM_001130448	C15orf62	chromosome 15 open reading frame 62
chr15_-_68781662	10.433	NM_001008224	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr19_-_43955984	10.406	NM_002307	LGALS7 LGALS7B	lectin, galactoside-binding, soluble, 7 lectin, galactoside-binding, soluble, 7B
chr4_-_122304925	9.969	NM_024873	TNIP3	TNFAIP3 interacting protein 3
chr11_+_12265022	9.962	NM_032867	MICALCL	MICAL C-terminal like
chr1_-_36589744	9.819
chr2_-_73170290	9.774		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr1_-_115682374	9.767	NM_002506	NGF	nerve growth factor (beta polypeptide)
chr9_+_676640	9.751
chr15_-_53996597	9.545	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr1_-_151788341	9.342	NM_002960	S100A3	S100 calcium binding protein A3
chr19_-_40711034	9.302	NM_001166034 NM_001166035 NM_198538	SBSN	suprabasin
chrX_+_99786044	9.212		SRPX2	sushi-repeat containing protein, X-linked 2
chr1_+_151270301	9.188	NM_003125	SPRR1B	small proline-rich protein 1B
chr14_+_20537253	9.148	NM_014579	SLC39A2	solute carrier family 39 (zinc transporter), member 2
chr16_+_56219802	9.135	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr12_+_13240983	8.954		EMP1	epithelial membrane protein 1
chr1_+_34993234	8.912	NM_005268	GJB5	gap junction protein, beta 5, 31.1kDa
chr1_-_108032645	8.847	NM_001079874	VAV3	vav 3 guanine nucleotide exchange factor
chr4_+_35959638	8.804	NM_001136536	DTHD1	death domain containing 1
chr10_-_88720908	8.779		LOC100133190	hypothetical LOC100133190
chr1_-_221920023	8.738	NM_001143962	CAPN8	calpain 8
chrX_+_99785818	8.737	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr10_-_105228986	8.614	NM_001129742	CALHM3	calcium homeostasis modulator 3
chr6_+_31190505	8.609	NM_014068	PSORS1C1	psoriasis susceptibility 1 candidate 1
chr11_-_119499188	8.601		TRIM29	tripartite motif containing 29
chr12_+_13240987	8.588		EMP1	epithelial membrane protein 1
chr1_-_117554999	8.536	NM_024626	VTCN1	V-set domain containing T cell activation inhibitor 1
chr5_-_149473127	8.450	NM_005211	CSF1R	colony stimulating factor 1 receptor
chr18_+_19706979	8.438	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr7_-_16811131	8.344	NM_006408	AGR2	anterior gradient homolog 2 (Xenopus laevis)
chr10_-_90601655	8.343	NM_144590	ANKRD22	ankyrin repeat domain 22
chr12_-_15706340	8.307		EPS8	epidermal growth factor receptor pathway substrate 8
chr2_+_36777336	8.279	NM_001177969 NM_001177970 NM_001177971 NM_001177972 NM_053276	VIT	vitrin
chr16_-_2848106	8.160	NM_022119	PRSS22	protease, serine, 22
chr1_+_34997928	8.152	NM_153212	GJB4	gap junction protein, beta 4, 30.3kDa
chr11_+_58146721	8.100	NM_000614	CNTF	ciliary neurotrophic factor
chr6_-_169392771	7.944
chr15_-_38417564	7.935		C15orf52	chromosome 15 open reading frame 52
chr16_+_65868913	7.811	NM_015432	PLEKHG4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr11_-_76676110	7.793	NM_182833	GDPD4	glycerophosphodiester phosphodiesterase domain containing 4
chr5_-_54317102	7.527	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr13_-_37070862	7.501	NM_001135934 NM_001135935 NM_001135936 NM_006475	POSTN	periostin, osteoblast specific factor
chr20_-_35586366	7.469	NM_001167823	BLCAP	bladder cancer associated protein
chr1_-_111908085	7.410	NM_001081976	ADORA3	adenosine A3 receptor
chr1_-_150564302	7.392	NM_002016	FLG	filaggrin
chr3_+_161877640	7.268	NM_025047	ARL14	ADP-ribosylation factor-like 14
chr4_+_146820805	7.194	NM_001080531	C4orf51	chromosome 4 open reading frame 51
chr1_-_28392966	7.100	NM_001164722 NM_001164721	PTAFR	platelet-activating factor receptor
chr16_+_70117523	7.088	NM_005769 NM_001166395	CHST4	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr17_-_7434113	7.057	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr1_-_221919982	7.031		CAPN8	calpain 8
chr10_+_88770025	7.022	NM_001146157	FAM25A	family with sequence similarity 25, member A
chr11_-_128399218	6.959	NM_014715	ARHGAP32	Rho GTPase activating protein 32
chr17_-_36928604	6.828	NM_002275	KRT15	keratin 15
chr3_-_127258299	6.805	NM_001008487	SLC41A3	solute carrier family 41, member 3
chr16_-_73859451	6.720	NM_001170715	BCAR1	breast cancer anti-estrogen resistance 1
chr1_+_81544432	6.630		LPHN2	latrophilin 2
chr11_-_102331643	6.629	NM_002427	MMP13	matrix metallopeptidase 13 (collagenase 3)
chr11_+_20005704	6.617		NAV2	neuron navigator 2
chr10_+_24795446	6.615		KIAA1217	KIAA1217
chr9_-_34652629	6.577	NM_006664	CCL27	chemokine (C-C motif) ligand 27
chr10_+_24795465	6.536		KIAA1217	KIAA1217
chr15_+_65245546	6.512	NM_001145104	SMAD3	SMAD family member 3
chr11_-_101906640	6.496	NM_002423	MMP7	matrix metallopeptidase 7 (matrilysin, uterine)
chr19_-_56164628	6.439	NM_002774	KLK6	kallikrein-related peptidase 6
chr2_-_202271598	6.422	NM_033066	MPP4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_+_151147646	6.275	NM_005547	IVL	involucrin
chr19_-_56204615	6.243	NM_012315	KLK9	kallikrein-related peptidase 9
chr10_+_47867667	6.207	NM_001137556 NM_001137549 NM_001137548	FAM25B FAM25G FAM25C	family with sequence similarity 25, member B family with sequence similarity 25, member G family with sequence similarity 25, member C
chr11_-_123353607	6.172	NM_001004474	OR10S1	olfactory receptor, family 10, subfamily S, member 1
chr1_+_181421796	6.074	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr3_-_150578207	5.948	NM_014220	TM4SF1	transmembrane 4 L six family member 1
chr11_-_102174102	5.942	NM_001145938 NM_002421	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr18_-_26996742	5.917	NM_004948 NM_024421	DSC1	desmocollin 1
chr2_+_219180862	5.901		PLCD4	phospholipase C, delta 4
chr11_-_102174032	5.901		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr19_+_43971689	5.896	NM_001042507	LGALS7B	lectin, galactoside-binding, soluble, 7B
chr2_-_18634257	5.877	NM_001002006 NM_033253	NT5C1B-RDH14 NT5C1B	NT5C1B-RDH14 readthrough 5'-nucleotidase, cytosolic IB
chr3_-_188936941	5.836	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr14_+_51025604	5.813	NM_001042481	FRMD6	FERM domain containing 6
chr15_+_38319326	5.796	NM_020168	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr19_-_50977485	5.792		DMPK	dystrophia myotonica-protein kinase
chr1_+_40508336	5.752		ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr1_+_181421984	5.720		LAMC2	laminin, gamma 2
chr6_+_41712907	5.712		MDFI	MyoD family inhibitor
chr18_-_45630154	5.705		MYO5B	myosin VB
chr7_+_1543644	5.669		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr3_-_48576204	5.563	NM_033199	UCN2	urocortin 2
chr22_-_41357380	5.518
chr4_-_152366970	5.495	NM_001009555 NM_001128923	SH3D19	SH3 domain containing 19
chr8_-_72431274	5.386	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr6_+_47732181	5.374	NM_153839	GPR111	G protein-coupled receptor 111
chr18_+_50646616	5.350	NM_004163	RAB27B	RAB27B, member RAS oncogene family
chr3_+_185520744	5.282	NM_004953	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr2_+_202379442	5.271	NM_139158	CDK15	cyclin-dependent kinase 15
chr11_-_8695974	5.260		ST5	suppression of tumorigenicity 5
chr1_+_151223180	5.206	NM_005987	SPRR1A	small proline-rich protein 1A
chr20_+_19903778	5.187		RIN2	Ras and Rab interactor 2
chr18_+_59295123	5.178	NM_002639	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr4_+_661710	5.056	NM_002477	MYL5	myosin, light chain 5, regulatory
chr5_+_59819761	5.045		PART1	prostate androgen-regulated transcript 1 (non-protein coding)
chr16_-_30983909	5.025	NM_001172669 NM_001172670	ZNF668	zinc finger protein 668
chr5_+_36644187	4.993	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_-_46601687	4.982	NM_001137556 NM_001137549 NM_001137548	FAM25B FAM25G FAM25C	family with sequence similarity 25, member B family with sequence similarity 25, member G family with sequence similarity 25, member C
chr6_-_152744143	4.968		SYNE1	spectrin repeat containing, nuclear envelope 1
chr2_+_69055208	4.952	NM_019617	GKN1	gastrokine 1
chr2_+_233605625	4.925	NM_005383	NEU2	sialidase 2 (cytosolic sialidase)
chr14_+_62740878	4.912	NM_020663	RHOJ	ras homolog gene family, member J
chr2_+_113591940	4.904	NM_000577 NM_173841 NM_173843	IL1RN	interleukin 1 receptor antagonist
chr4_-_54119159	4.886	NM_032622	LNX1	ligand of numb-protein X 1
chr1_+_150753601	4.855	NM_019060	CRCT1	cysteine-rich C-terminal 1
chr5_+_73145098	4.838		RGNEF	190 kDa guanine nucleotide exchange factor
chr12_-_90097384	4.830	NM_133503	DCN	decorin
chr10_+_118177371	4.799	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr11_-_62213946	4.798	NM_203422	LRRN4CL	LRRN4 C-terminal like
chr9_-_129381086	4.782	NM_001035534	FAM129B	family with sequence similarity 129, member B
chr4_-_151990061	4.779		LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr3_+_190147633	4.759		TPRG1	tumor protein p63 regulated 1
chr21_+_25856311	4.748		MIR155HG	MIR155 host gene (non-protein coding)
chrX_-_33139349	4.720	NM_004006	DMD	dystrophin
chr1_-_159325709	4.712		PVRL4	poliovirus receptor-related 4
chr4_+_76700281	4.700	NM_178497	C4orf26	chromosome 4 open reading frame 26
chr5_+_35892747	4.678	NM_002185	IL7R	interleukin 7 receptor
chr4_-_100575313	4.644	NM_001166504 NM_000673	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_+_106498763	4.635	NM_001017523	BTBD11	BTB (POZ) domain containing 11
chr16_-_30032330	4.620	NM_024307	GDPD3	glycerophosphodiester phosphodiesterase domain containing 3
chr19_-_50977592	4.613	NM_001081560 NM_001081562 NM_004409	DMPK	dystrophia myotonica-protein kinase
chr2_+_166034402	4.611	NM_001172173	CSRNP3	cysteine-serine-rich nuclear protein 3
chr9_-_90983501	4.603	NM_016848	SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr6_+_108593907	4.598	NM_003269	NR2E1	nuclear receptor subfamily 2, group E, member 1
chr17_-_53335748	4.587	NM_017949	CUEDC1	CUE domain containing 1
chr2_+_169634330	4.538		DHRS9	dehydrogenase/reductase (SDR family) member 9
chr5_-_59819642	4.520	NM_001165899	PDE4D	phosphodiesterase 4D, cAMP-specific
chr3_+_185521139	4.509		EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr12_-_105057940	4.504	NM_014840	NUAK1	NUAK family, SNF1-like kinase, 1
chr22_-_43986896	4.449		KIAA0930	KIAA0930
chr15_+_39918302	4.440	NM_001114633	PLA2G4B	phospholipase A2, group IVB (cytosolic)
chr9_+_35663852	4.433	NM_001216	CA9	carbonic anhydrase IX
chr3_-_150578148	4.432		TM4SF1	transmembrane 4 L six family member 1
chr6_+_30964441	4.421	NM_013994	DDR1	discoidin domain receptor tyrosine kinase 1
chr3_-_197549640	4.389	NM_138461	TM4SF19	transmembrane 4 L six family member 19
chr19_-_50977586	4.387		DMPK	dystrophia myotonica-protein kinase
chr19_-_60573552	4.335	NM_000641	IL11	interleukin 11
chr3_+_101720753	4.327		TMEM45A	transmembrane protein 45A
chr20_+_34206070	4.321	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr3_-_197549588	4.309		TM4SF19	transmembrane 4 L six family member 19
chr8_-_143848225	4.232	NM_177458	LYNX1	Ly6/neurotoxin 1
chrX_-_19598912	4.226	NM_001184960	SH3KBP1	SH3-domain kinase binding protein 1
chr1_+_181422016	4.223		LAMC2	laminin, gamma 2
chr10_-_48877824	4.222	NM_001137556 NM_001137549 NM_001137548	FAM25B FAM25G FAM25C	family with sequence similarity 25, member B family with sequence similarity 25, member G family with sequence similarity 25, member C
chr3_+_64645819	4.188		LOC100507098	hypothetical LOC100507098
chr3_-_150578103	4.186		TM4SF1	transmembrane 4 L six family member 1
chr17_-_37034288	4.174	NM_000422	KRT17	keratin 17
chr1_+_24518501	4.133	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr4_+_40032146	4.113	NM_017581	CHRNA9	cholinergic receptor, nicotinic, alpha 9
chr11_-_62213577	4.111		LRRN4CL	LRRN4 C-terminal like
chr9_-_116920232	4.110	NM_002160	TNC	tenascin C
chr10_-_116241572	4.088
chr1_+_151025376	4.062	NM_178353	LCE1E	late cornified envelope 1E
chr10_-_31328426	4.049	NM_001143769	ZNF438	zinc finger protein 438
chr10_-_62002672	4.047		ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_74462226	4.026	NM_001159587 NM_001159588 NM_133493	CD109	CD109 molecule
chr15_+_84021271	4.024	NM_144767	AKAP13	A kinase (PRKA) anchor protein 13
chr13_-_85271329	4.017	NM_032229	SLITRK6	SLIT and NTRK-like family, member 6
chr13_+_96592051	3.995		MBNL2	muscleblind-like 2 (Drosophila)
chr3_-_58175437	3.960	NM_004944	DNASE1L3	deoxyribonuclease I-like 3
chr1_+_24518398	3.932	NM_198173 NM_198174	GRHL3	grainyhead-like 3 (Drosophila)
chr19_-_48661563	3.927	NM_014400	LYPD3	LY6/PLAUR domain containing 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.65	1.83e-03	GO:0009888	tissue development
1.30	2.83e-03	GO:0048856	anatomical structure development
1.31	5.15e-03	GO:0048731	system development
1.38	1.29e-02	GO:0048513	organ development
1.58	1.55e-02	GO:0009611	response to wounding

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.36	1.37e-03	GO:0005576	extracellular region
1.48	8.61e-03	GO:0044421	extracellular region part
1.37	1.88e-02	GO:0005856	cytoskeleton
5.10	3.05e-02	GO:0001533	cornified envelope
2.49	3.31e-02	GO:0044449	contractile fiber part
1.84	3.45e-02	GO:0005578	proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.50	2.50e-03	GO:0030414	peptidase inhibitor activity
2.55	2.54e-03	GO:0004866	endopeptidase inhibitor activity
2.45	5.65e-03	GO:0061135	endopeptidase regulator activity
2.89	1.45e-02	GO:0004867	serine-type endopeptidase inhibitor activity
1.85	1.53e-02	GO:0004175	endopeptidase activity
1.14	1.85e-02	GO:0005515	protein binding
2.17	3.11e-02	GO:0061134	peptidase regulator activity